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And so, unfortunately, COVID kind of retaliated in terms of this inflammation and revving up of the clotting system." But when blood clots happen when they're not supposed to, that's when people get these DVTs and PEs. For example, if you cut yourself you want your clotting system to be revved up and make a scab and stop that bleeding. And, essentially, we think it has to do with lots of different pathways, whereby the virus, once it attaches and gets in, can kind of create this inflammatory state in this relationship between inflammation and coagulation and really revving up your clotting system when it shouldn't be revved up. And there is this incredible association between patients with COVID-19 and blood clots. And I would say, one of the silver linings is that, I think, it has raised awareness about blood clots because it's in the news. Rosovsky: "COVID-19 has obviously been quite devastating.

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What is the relationship, at least what do we know about the relationship, between COVID-19 and blood clots?" We've learned so much about it, but there's still a lot we don't know, and it affects us in some really surprising ways. COVID-19 is a virus that affects the body in so many different ways. Because, of course, that is something that we've heard a lot about this year. Nebbe: "Let's talk about blood clots and COVID-19. And then, unless there's a reason you're not allowed to keep yourself hydrated, keeping yourself hydrated is really important as well." The other thing is, usually, when people are in the hospital, they try to encourage people to get out of bed and walk around, again, if that can be done safely. If the hospital is not having that be a priority, and you're in the hospital, and you're sitting around and bed-bound and immobile, just had surgery, just had anesthesia, if it's safe for you, you're not at a big bleeding risk, then absolutely it's something to ask your doctor. Is that something that, if we are in the hospital, we should ask our doctor about?" That's something that medical teams are aware of, and, if this seems to be a risk factor, should treat. Nebbe: "When people are in the hospital, that puts them at greater risk for developing blood clots. This interview has been edited for length and clarity. She joined the conversation to talk about the risks associated with blood clots and COVID-19. Rachel Rosovsky is the director of thrombosis research in the division of hematology at Massachusetts General Hospital and an assistant professor at the Harvard Medical School. You can find that entire conversation here. On Talk of Iowa, host Charity Nebbe spoke with experts about some of the risk factors and the relationships between blood clots and other diseases. Up to 100,000 Americans die every year due to deep vein thrombosis (DVT) or pulmonary embolism (PE).







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